How Transnetyx Helps Labs Meet Modern Funding and Compliance Expectations
The 21st Century Cures Act represents a pivotal shift in how biomedical research is funded, evaluated, and sustained. Beyond accelerating innovation, the Act sets clear expectations for scientific rigor, reproducibility, and responsible animal use—raising the bar for how research programs must operate to remain competitive for federal funding.
For many labs, the challenge lies not in understanding these requirements, but in turning them into daily, auditable practices. Transnetyx helps bridge that gap by embedding Cures Act–aligned tools directly into the foundation of animal research programs.
What the 21st Century Cures Act Means for Research Programs
The Act emphasizes three core priorities that directly impact animal-based research:
Reducing unnecessary animal use through validated alternatives
Improving scientific rigor and reproducibility
Ensuring reliable, traceable research data through defined policies
Meeting these expectations requires more than policy statements—it requires systems that generate transparency, consistency, and defensible data at every stage of research.
Operationalizing Cures Act Requirements with Transnetyx
As a strategic partner to individual labs and institutions, Transnetyx provides a comprehensive suite of services designed to make compliance practical, scalable, and sustainable.
Our Automated Genotyping, Genetic Monitoring, and Microbiome Analysis, paired with predictive colony management software (Colony+AMI) and our real-time compliance platform (tick@lab), give labs complete visibility and control over their animal programs—helping them demonstrate readiness for continued funding.
How Transnetyx Supports Key Sections of the 21st Century Cures Act
Section 2034(d): Reducing Animal Use Through Validated Alternatives:
The Cures Act calls for minimizing animal use whenever possible. Transnetyx enables this by combining predictive colony analytics with Automated Genotyping, allowing labs to breed only the animals they truly need. By aligning breeding decisions with real experimental demand, labs can significantly reduce surplus animals and associated ethical and operational burdens.
Section 3021: Improving Scientific Rigor and Reproducibility:
Reproducibility depends on accurate tracking, clear documentation, and data-driven decisions. Colony+AMI provides real-time animal tracking, comprehensive audit trails, and decision-support tools that link colony data directly to study design—helping labs demonstrate rigor at every step.
Section 2039: Ensuring Reliable and Reproducible Research Data:
Defined policies and consistent genetic verification are essential for data integrity. Genetic Monitoring delivers a systematic approach to confirming genetic consistency, identifying contamination, and safeguarding long-term data reliability—ensuring research outputs stand up to scrutiny.
Supporting Funding Readiness While Improving Daily Operations
Compliance with the 21st Century Cures Act should not come at the expense of productivity or staff well-being. Transnetyx solutions are designed to reduce manual workloads, streamline workflows, and alleviate the emotional strain associated with overbreeding and culling.
By embedding these tools into daily operations, labs can:
Improve confidence in regulatory readiness
Reduce technician strain through automation
Support PIs with clear, defensible data for grant applications